Table 1.
Motifs with significantly greater co-occurrence in correlated enhancers than expected (after filtering—see text)
| Motif | Co-occurrence Score | P-value | q-value | Gene |
|---|---|---|---|---|
| M00649 | 9.80E-02 | 0 | 1.70E-04 | MAZ |
| M01742 | 1.20E+00 | 0 | 2.10E-04 | Zfp206 |
| M00986 | 3.90E-02 | 0 | 3.00E-04 | Churchill |
| M00915 | 5.40E-01 | 0 | 3.80E-04 | AP-2 |
| M01028 | 2.70E+00 | 0 | 4.30E-04 | NRSF |
| M01783 | 6.30E-01 | 0 | 4.70E-04 | SP2 |
| M00431 | 1.30E-01 | 0 | 5.10E-04 | E2F-1 |
| M00008 | 3.30E-01 | 0 | 5.60E-04 | Sp1 |
| M01199 | 6.90E-01 | 0 | 6.00E-04 | RNF96 |
| M01219 | 4.60E-01 | 0 | 6.40E-04 | SP1:SP3 |
| M00925 | 5.40E-02 | 0 | 7.30E-04 | AP-1 |
| M01253 | 7.50E-01 | 0 | 8.10E-04 | CNOT3 |
| M00189 | 6.80E-01 | 0 | 9.00E-04 | AP-2 |
| M00255 | 3.70E-01 | 0 | 9.40E-04 | GC_box |
| M01482 | 2.60E+00 | 0 | 9.80E-04 | Nkx3-2 |
| M00716 | 8.20E-01 | 0 | 1.00E-03 | ZF5 |
| M01267 | 6.40E-02 | 0 | 1.10E-03 | FRA1 |
| M00199 | 9.20E-02 | 0 | 1.10E-03 | AP-1 |
| M00196 | 6.30E-01 | 0 | 1.20E-03 | Sp1 |
| M00800 | 8.00E-01 | 0 | 1.20E-03 | AP-2 |
| M00807 | 3.20E-01 | 0 | 1.30E-03 | Egr |
| M00931 | 4.80E-01 | 0 | 1.30E-03 | Sp1 |
| M00933 | 3.20E-01 | 0 | 1.40E-03 | Sp1 |
| M00932 | 5.90E-01 | 0 | 1.40E-03 | Sp1 |
| M00615 | 1.90E+00 | 0 | 1.50E-03 | c-Myc:Max |
| M01303 | 3.10E-01 | 0 | 1.50E-03 | SP1 |
| M01588 | 2.90E-01 | 0 | 1.50E-03 | GKLF_(KLF4) |
| M00322 | 4.30E-01 | 0 | 1.60E-03 | c-Myc:Max |
| M00976 | 2.20E-01 | 0 | 1.60E-03 | AhR,_Arnt,_ HIF-1 |
| M00720 | 7.80E-02 | 0 | 1.70E-03 | CAC-binding_ protein |
| M01273 | 4.50E-01 | 0 | 1.70E-03 | SP4 |
| M01837 | 1.70E-01 | 0 | 1.80E-03 | FKLF |
| M00174 | 1.10E-01 | 1.10E-16 | 1.90E-03 | AP-1 |
| M00926 | 3.80E-02 | 4.40E-16 | 1.90E-03 | AP-1 |
| M00428 | 4.60E-02 | 6.70E-16 | 2.00E-03 | E2F-1 |
| M01593 | 9.50E-01 | 1.20E-15 | 2.10E-03 | Zfx |
| M01104 | 4.60E-02 | 2.20E-14 | 2.10E-03 | MOVO-B |
| M01177 | 3.20E-01 | 1.50E-11 | 2.10E-03 | SREBP2 |
| M01230 | 2.40E-02 | 1.60E-11 | 2.20E-03 | ZNF333 |
| M01816 | 1.30E-01 | 5.60E-11 | 2.20E-03 | ZBP89 |
| M00940 | 5.50E-01 | 4.10E-10 | 2.30E-03 | E2F-1 |
| M01597 | 2.20E-01 | 9.70E-10 | 2.30E-03 | Zfp281 |
| M01045 | 3.90E-01 | 2.70E-09 | 2.40E-03 | AP-2alphaA |
| M01162 | 3.00E-02 | 1.20E-08 | 2.40E-03 | OG-2 |
| M01292 | 2.00E-02 | 1.50E-08 | 2.40E-03 | HOXA13 |
| M00378 | 9.90E-02 | 1.30E-07 | 2.50E-03 | Pax-4 |
| M00982 | 6.80E-01 | 2.00E-07 | 2.60E-03 | KROX |
| M00644 | 3.30E-02 | 3.70E-07 | 2.60E-03 | LBP-1 |
| M01714 | 3.50E-01 | 4.70E-07 | 2.70E-03 | KLF15 |
| M01275 | 2.40E-02 | 9.80E-07 | 2.70E-03 | IPF1 |
| M01318 | 1.40E+00 | 1.60E-06 | 2.70E-03 | Irx-3 |
| M00175 | 4.70E-02 | 1.90E-06 | 2.80E-03 | AP-4 |
Column 1: TRANSFAC Motif ID, Column 2: Co-occurrence score (see text), Column 3: P-value, Column 4: Multiple testing corrected q-value, Column 5: TF name.