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. Author manuscript; available in PMC: 2013 Aug 8.
Published in final edited form as: J Orthop Res. 2011 Aug 1;30(2):288–295. doi: 10.1002/jor.21501

Figure 4. hInhA overexpression increases endosteal new bone formation during DO.

Figure 4

(A) MicroCT reconstruction of mouse tibiae. (Top) Swiss-Webster treated with vehicle or hInhA for 18 days. (Bottom) Glvp/InhA mice treated with Vehicle or MFP to overexpress hInhA. Mice were sacrificed 18 days post-operatively and the DO gap scanned. (B) MicroCT translucent reconstructions illustrate hInhA effects on endosteal bone volume. 3-Dimensional reconstruction of endosteal new bone in Vehicle treated (yellow) and InhA overexpressing (gray) Glvp/InhA mice. (C) Total volume and bone volume of the endosteal distraction gap were calculated directly from the voxel volumes in the reconstruction. Data shown are mean +/− SD; *=P<0.05.