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. Author manuscript; available in PMC: 2013 Aug 8.
Published in final edited form as: Anticancer Res. 2012 Aug;32(8):3103–3113.

Figure 1.

Figure 1

Cytotoxicity of β-elemene towards human ovarian epithelial IOSE-397 cells, cisplatin-sensitive human ovarian cancer A2780 cells, and cisplatin-resistant human ovarian cancer A2780/CP cells. Exponentially growing cells were treated with β-elemene at the indicated concentrations (20–200 μg/ml) for 24, 48, 72, and 96 h. A and B: Cell survival was assessed by the MTT assay, as described in the Materials and Methods. Cell growth values are expressed in relation to growth of untreated cells (100%). C: Average half maximal inhibitory concentration (IC50) values of β-elemene were 113 μg/ml for IOSE-397 cells, 65 μg/ml for A2780 cells, and 75 μg/ml for A2780/CP cells. The results represent the means±SD of at least three independent experiments. #p<0.01 vs. IOSE-397 cells.