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. Author manuscript; available in PMC: 2014 Jul 1.
Published in final edited form as: J Allergy Clin Immunol. 2013 Jun 2;132(1):3–13. doi: 10.1016/j.jaci.2013.04.039

Table 2.

Potential utility of miRNAs in allergic diseases

1. Coordinately targeting key pathways, such as the polarization of adaptive
immune responses, by several miRNAs
2. Reversal of an established disease phenotype
3. Combinatorial targeting of a key mRNA by several miRNAs
4. Regulating the epigenetic machinery
5. Serving as biomarkers for disease diagnosis, stratification, and prognosis
6. Development as potential therapeutic targets