Skip to main content
. Author manuscript; available in PMC: 2013 Aug 8.
Published in final edited form as: Semin Respir Crit Care Med. 2009 Jul 24;30(4):386–398. doi: 10.1055/s-0029-1233308

Figure 3.

Figure 3

Wild-type BMPR2 transcript levels, as measured by relative real-time polymerase chain reaction (PCR) analysis, in affected and unaffected BMPR2 mutation carriers. This study includes four distinct families with four different types of BMPR2 mutations predicted to have a haploinsufficient effect due to the activation of the nonsense-mediated decay pathway. Note the lower relative BMPR2 expression among affected carriers, as compared with unaffected carriers. Adapted from Hamid et al.66 Reproduced with permission of John Wiley & Sons, Inc.