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. Author manuscript; available in PMC: 2013 Aug 8.
Published in final edited form as: Cell. 2009 May 15;137(4):609–622. doi: 10.1016/j.cell.2009.04.050

Figure 1. Overview of p53 Posttranslational Modifications.

Figure 1

More than 36 amino acids of p53 are reported to be modified. The major sites of p53 phosphorylation (P), ubiquitination (Ub), and acetylation (Ac) are shown with the corresponding major modifying enzymes and signals. Furthermore, additional phosphorylation and acetylation sites, as well as major sites of methylation (Me), sumoylation (S), neddylation (N8), glycosylation (O-Glc), and ribosylation (ADP), are indicated.