Figure 2.
Characteristics of [18F]FP-(+)-DTBZ metabolism and availability in arterial blood. (A) The fraction of radioactivity in plasma attributable to the parent compound was not statistically different between groups (0.23<P< 0.94 for t tests at each individual time point; P=0.36 for two-way ANOVA across time points common to all subjects). Data are expressed as mean ± s.d. (B) Fraction of radiotracer unbound to plasma proteins did not differ between groups (0.224±0.030 vs. 0.217±0.018, P=0.53). Horizontal lines represent mean for the respective cohort. Open markers: control subjects. Filled markers: T1DM patients.