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. Author manuscript; available in PMC: 2013 Aug 8.
Published in final edited form as: J Nucl Med. 2012 May 9;53(6):908–916. doi: 10.2967/jnumed.111.100545

Figure 5.

Figure 5

Tracer binding density was associated with insulin secretory capacity. The pancreatic [18F]FP-(+)-DTBZ uptake and binding density parameters SUV (A), VT (B) and BPND (C) correlated positively with arginine-stimulated increases in circulating C-peptide, a metric of β-cell function. Multiplying [18F]FP-(+)-DTBZ binding density parameters by pancreas volume to reflect total pancreatic binding improved their quantitative relationships with insulin secretory capacity (D–F). Data from T1DM patients indicated by filled markers, control subjects by open markers.