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. Author manuscript; available in PMC: 2013 Aug 8.
Published in final edited form as: J Immunol. 2011 Apr 15;186(10):5675–5686. doi: 10.4049/jimmunol.1003711

FIGURE 1.

FIGURE 1

LD between HLA-A*7401 and other class I alleles in southern African populations. A, All HLA-B and HLA-Cw alleles that are significantly linked to HLA-A*7401 in a pooled cohort from South Africa (Durban, Bloemfontein, and Kimberley cohorts, n = 1510) and in Botswana (n = 514) are shown. The p values were calculated by Fisher’s exact test and corrected for multiple comparisons using the Bonferroni approach, using the online tool at: http://www.hiv.lanl.gov/content/immunology/hla/hla_linkage.html. No significant linkage associations were identified for HLA-A*7401 among Zimbabweans recruited via the Thames Valley cohort (n = 73, data not shown). All subjects with HLA-B*35 are pooled together as HLA-B*35(01). B, Percentage of HLA-A*7401+ subjects with HLA-B*5703 in each of five southern African cohorts. Statistically significant LD between these alleles is present only in the Durban cohort.