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. Author manuscript; available in PMC: 2013 Aug 8.
Published in final edited form as: J Immunol. 2011 Apr 15;186(10):5675–5686. doi: 10.4049/jimmunol.1003711

FIGURE 3.

FIGURE 3

Effect of combinations of HLA-A*7401 and HLA-B*5703 on viral load. A and B, Viral load (RNA copies/ml plasma) of C-clade–infected adult study subjects from all study subjects (A) and Durban (B), in the presence and absence of HLA-B*5703 and HLA-A*7401. Boxes show median, 25th and 75th percentile; whiskers 10th–90th percentile. The p values were by Mann–Whitney U test. C and D, Subjects with HLA-B*5703 ranked by viral load and divided by quartiles into four interquartile (IQ) pools for all study subjects (n = 97) (C) and Durban (n = 55) (D). The proportion of each of the four subgroups with HLA-A*7401 is shown, demonstrating that HLA-A*7401 is enriched in the IQ pool with the lowest viral loads. The p values were by Fisher’s exact test.