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. Author manuscript; available in PMC: 2013 Aug 8.
Published in final edited form as: J Immunol. 2011 Apr 15;186(10):5675–5686. doi: 10.4049/jimmunol.1003711

FIGURE 7.

FIGURE 7

Relation between HLA-A*7401 status and frequency of HLA-B*5703–restricted CD8+ T cell mutations/IFN-γ ELISPOT responses. A, Frequency of HLA-B*5703–selected Gag polymorphisms [defined by previous studies (3, 6, 16, 17)], in 64 subjects with HLA-B*5703 according to the presence/absence of HLA-A*7401. p24-Gag sequences from Bloemfontein (n = 8), Durban (n = 38), Gaborone (n = 11), and Thames Valley cohorts (n = 7), with sequence data available for TW10 (n = 63), KF11 (n = 64), ISW9 (n = 63), and all three epitopes (n = 62). B, Frequency of IFN-γ ELISPOT response to three HLA-B*5703 epitopes in p24-Gag in 46 subjects with HLA-B*5703 according to the presence or absence of HLA-A*7401. The p values were by Fisher’s exact test. Data from Durban (n = 31) and Thames Valley cohorts (n = 15).