Table III.
Sequences of HLA-A*7401 and related HLA-A alleles at the B and F pockets of the peptide binding groove and predicted residues bound at these positions
| Residues Determining B Pocket
|
(Predicted) Residue at P2 | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 7 | 9 | 24 | 25 | 34 | 45 | 63 | 66 | 67 | 70 | 99 | ||
| HLA-A consensus | Y | F | A | V | V | M | E | N | V | H | Y | |
| HLA-A*0101 | — | — | — | — | — | — | — | — | M | — | — | T/S/I/M |
| HLA-A*3201 | — | — | — | — | — | — | — | — | — | — | — | (I/M) |
| HLA-A*7401 | — | — | — | — | — | — | — | — | — | — | — | (L/I/M/Q) |
| Residues Determining F Pocket
|
(Predicted) Residue at PC | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| 77 | 80 | 81 | 84 | 95 | 116 | 123 | 143 | 146 | 147 | ||
| HLA-A consensus | D | T | L | Y | I | D | Y | T | K | W | |
| HLA-A*3303 | — | — | — | — | — | — | — | — | — | — | R |
| HLA-A*6601 | — | — | — | — | — | — | — | — | — | — | R/K |
| HLA-A*6801 | — | — | — | — | — | — | — | — | — | — | R/K |
| HLA-A*7401 | — | — | — | — | — | — | — | — | — | — | (R/K) |