Table 1. Experimentally determined allosteric activators of PYKs^*.

Organism	Modifier					References
	Activation		No Activation	Inhibition
	ligand	k0.5v [mM]		ligand	k0.5v [mM]
Escherichia coli	FBP	0.04	G6P, F6P	-	-	[17], [76]
Streptococcus	G6P,	0.04	F6P	Pi	-	[19]
mutans	(R5P)$	0.41
Lactococcus	G6P,	0.012	-	Pi	1.3	[13], [32]
lactis	R5P,	0.015
	F6P,	0.03
	FBP,	0.057
	Gal6P	0.45

^*k_0.5v values are dependent on the experimental conditions. See references for further information.

^$partial activation by R5P.