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. Author manuscript; available in PMC: 2014 Sep 1.
Published in final edited form as: Cell Microbiol. 2013 Mar 28;15(9):1572–1584. doi: 10.1111/cmi.12135

Figure 3.

Figure 3

Expression (qPCR) of cell surface receptors and cytokines of macrophages infected with strains of C. albicans at 1 and 2 h (A and B, respectively). The macrophage receptors, Dectin-1, TLR-2 and TLR-4 usually synergize to trigger downstream cytokine and adaptor protein expression after binding to ligands such as β-glucan, phospholipomannan and O-linked mannosyl residues. Less expression of receptors occurred in co-culture with goa1Δ, while the cytokines, IL-6, IL-10, IFN-γ and adaptor protein MyD88 were significantly decreased at 1h. (C) The concentration of IL-6 was also determined by ELASA in the supernatants of RAW264.7 cells infected with all yeast strains for 3h to verify the qPCR expression profile. (*P< 0.05; **P< 0.01).