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. 2013 Jun 18;109(3):777–779. doi: 10.1038/bjc.2013.309

Table 2. Comparison of characteristics of BRCA-positive patients in clinical stream and population-based stream.

  Clinical referral genetic testing (n=22) Jewish population genetic testing (n=68) Univariate P
Mean age (years)
46.1 (28–71)
44.2 (24–68)
0.51
Personal history of cancer
Any 9 (23.6%) 0 (0.0%) <0.0001
Ovary      
Breast      
None
 
 
 
Ethnic group
Jewish 3 68 <0.0001
Other white 18 0  
Asian 0 0  
Black 1 0  
Other
0
0
 
First-degree relative with ovarian cancer
6 of 22 (27.2%)
3 of 68 (4.4%)
0.006
First-degree relative with breast cancer
13 of 22(59.1%)
8 of 68 (11.8%)
<0.0001
Proband met Ontario genetic testing criteria
22 of 22 (100%)
26 of 68 (38.2%)
<0.0001
Mutation (proband)
BRCA1 10 (45.5%) 25 (36.8%) 0.62
BRCA2 12 (54.6%) 43 (63.2%)