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Assessment of PF-03084014 on apoptosis. (A) Post gene array 3 days after PF-03084014 treatment on gene expression of apoptotic genes in CRC001-sensitive explant. (B) Western blot analysis of cleaved Notch1, cleaved caspase 3, cleaved PARP, phos p65, and BCLxL in CRC021 2 h, 8 h, 24 h and 8 days after treatment with PF-03084014.
