Table 2. Multivariate analysis of the repeated measures.

Measure	Source	F-value	P-value
E2	Time	2.884	0.038**
	Time*group	1.735	0.162
	Group	9.949	0.002*
Breast density (%)	Time	90.371	<0.001
	Time*group	0.633	0.483
	Group	6.172	0.015**
Endometrial thickness	Time	2.071	0.122
	Time*group	12.521	<0.001
	Group	22.671	<0.001
TG	Time	1.091	0.353
	Time*group	1.671	0.173
	Group	0.845	0.360
Chol	Time	0.129	0.911
	Time*group	0.540	0.616
	Group	0.463	0.498
LDL	Time	0.420	0.758
	Time*group	1.578	0.190
	Group	0.115	0.736
HDL	Time	1.262	0.287
	Time*group	1.013	0.388
	Group	0.032	0.857

Abbreviations: Chol=cholesterol; E2=estradiol; HDL=high-density lipoprotein; LDL=low-density lipoprotein; TG=triglyceride.

Note: Time and time*group showed within-subject effects. Group showed between-subject effects. *P<0.01. **P<0.05.