Figure 4.

Proportions of newly born neurons (BrdU+/NeuN+) within the inner, intermediate and outer third of the DG granule cell layer. The proportion of newly born neurons found in the inner third was significantly different across the groups (ANOVA; p=0.03). Post Hoc comparisons between groups revealed that: while in sham treated controls the majority of newly born neurons were found in the inner third of the granular layer, this proportion was significantly lowered in trauma only animals (p<0.05 vs Sham). The proportion of newly born neurons found in the intermediate third also significantly varied across groups (ANOVA, p=0.004). The percentage of new born neurons found in the intermediate third layer was significantly higher in animal that received trauma only as compared to sham (p<0.01), irradiation only (p<0.05) or animals that received combined injury animals (p <0.05).