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NFAT activity in HeLa cells stimulated with or without TPA and ionomycin was inhibited by treatment with pomegranate extract and its components, punicalagin and ellagic acid. Values are means ± SDs, n = 3. Means within a group without a common letter differ, P < 0.05. C, control; NFAT, nuclear factor of activated T cells; TPA, 12-O-tetradecanoylphorbol-13-acetate; V, vehicle.
