FIGURE 3.

The urinary metabolites in male and female mice fed WB or CTRL diets for 6 wk. The scatter plot from the orthogonal projection to latent structure analysis is shown for urine samples from male WB-fed and CTRL-fed mice (A) and female WB-fed and CTRL-fed mice (B). Variables having a p(corr)[1] value >0.8 or <−0.8 are shaded gray in the loadings plots from males (C) and females (D). Variables depleted in WB-fed males did not meet the cutoff criteria and are therefore not shown. p[1] is a measure of covariance and p(corr)[1] a measure of model fit. White circles indicate variables that met the cutoff criteria in one gender but not the other. Variable labels I, II, III, IV, and V are described in Table 1. Values for A and B are individual data points for n = 4–6 mice/group and treatment. CTRL, control; PC, principal component; WB, white button.