Fig. 1.

MR imaging studies of the patient. Brain MRI demonstrated multiple cerebral infarctions, including a subacute lesion in the right frontal deep white matter, which appeared as a high signal on DWI and a low signal on the calculated ADC map (a, b). However, the corresponding mean DK image shows the peripherally high intensity and dark dot in the stroke lesion (c). The mean DK values for high intensity and dark dot are 1.596 and 0.591, respectively. Two weeks later, repeated MR scanning revealed a homogenous high signal on both DWI and the ADC map (d, e) and partially normalized mean DK (f) in the corresponding ischemic lesion. The mean DK value for the normalized area is 0.842. In the FLAIR image taken 6 months later (g), the stroke lesion revealed a low signal in the central cystic portion, with peripheral high intensity, as in the first DK image