Table 4.
Age-, site-, and FN BMD-adjusted hazard ratios (95 % CI) of predictors with incident hip fractures identified through SOF only vs. SOF or claims among FFS enrollees
| Predictor | Hazard ratio (95 % CI)
|
|
|---|---|---|
| Incident hip fracture in SOF (N=472 fractures) | Incident hip fracture in SOF or claims (N=602 fractures) | |
| 6-m walk time: tertiles | ||
| 1st tertile | 1.58 (1.23–2.02) | 1.52 (1.23–1.87) |
| 2nd tertile | 1.30 (1.02–1.66) | 1.18 (0.95–1.46) |
| 3rd tertile | 1.0 (ref) | 1.0 (ref) |
| Used arms to stand up from a chair (yes/no) | 1.26 (0.73–2.16) | 1.45 (0.90–2.33) |
| GDS depression score (+2.2) (higher= worse) | 1.10 (1.00–1.20) | 1.09 (1.01–1.18) |
| GDS ≥6, depressed (yes/no) | 0.82 (0.49–1.38) | 0.89 (0.58–1.39) |
| MMSE score, (−1.6 U) | 1.07 (0.99–1.17) | 1.15 (1.07–1.24) |
| Trails B score (+64 s) (using trimmed trails B variable) | 1.18 (1.08–1.29) | 1.19 (1.10–1.28) |
| Lives with others (yes/no) | 1.32 (1.08–1.60) | 1.22 (1.03–1.45) |
| Femoral neck BMD (−0.11 g/cm3) | 2.16 (1.92–2.43) | 2.23 (2.01–2.48) |
| Body mass index (−4.6 kg/m2) | 1.03 (0.93–1.15) | 1.01 (0.91–1.11) |
| Change in weight since age 25 (−19.5 %) | 1.10 (0.98–1.23) | 1.05 (0.96–1.16) |
| Prior clinical fractures (yes/no) | 1.22 (1.01–1.47) | 1.18 (1.00–1.39) |
| Fair/poor/very poor vs. good/excellent health status | 1.03 (0.80–1.32) | 1.06 (0.85–1.32) |
| IADL score (+1) | 1.12 (1.04–1.21) | 1.09 (1.02–1.17) |
| Any IADL impairment (yes/no) | 1.34 (1.10–1.61) | 1.31 (1.11–1.55) |
| Current smoker (yes/no) | 1.32 (0.96–1.81) | 1.07 (0.79–1.43) |
| Medical conditions (yes/no) | ||
| History of stomach surgery | 1.32 (0.68–2.56) | 1.37 (0.77–2.44) |
| Use of thyroid hormone pills | 1.39 (1.07–1.80) | 1.41 (1.11–1.77) |
| Type II diabetes mellitus | 1.70 (1.21–2.39) | 1.74 (1.29–2.34) |
| COPD | 1.13 (0.84–1.52) | 1.09 (0.84–1.43) |
| Parkinson’s disease | 1.98 (0.88–4.46) | 2.11 (0.99–4.49) |
| Lowest quartile distant depth perception | 1.23 (1.00–1.50) | 1.22 (1.02–1.46) |
| Contrast sensitivity (per 1 SD decrease) | 1.10 (0.76–1.59) | 1.12 (0.80–1.56) |
N for analyses is 4,248 alive, enrolled in SOF, who had femoral neck BMD measured at the second SOF visit, and enrolled in Medicare Fee for Service on 1/1/1991. All analyses were adjusted for age, femoral neck BMD, and clinic site. Associations significant at P<0.05 level were italicized