Fig. 3.
Energy production in working C57Bl/6 mouse hearts perfused in the absence (control) or in the presence of IVA with or without atrial pacing. Data are expressed as means ± SE of 4 –5 hearts. Rates of ATP production in cytosol and mitochondria are calculated from the measured rates of 1) glycolysis and 2) MV̇O2, (assuming an ATP/O ratio of 2.83), respectively, and are expressed per minute (A and B) and per beat (C and D). *P < 0.05 vs. control group; $P < 0.05 IVA vs. IVA + pacing group.