Skip to main content
. 2013 Aug 8;8(8):e71702. doi: 10.1371/journal.pone.0071702

Figure 1. OLE restores cognitive performance in 3.5–6 month-old TgCRND8 mice.

Figure 1

(A) Step down test: one-way ANOVA plus Bonferroni’s post comparison test shows a statistically significant increase in the mean retention latencies in untreated and OLE-treated wt and in OLE-treated Tg mice, as compared to their respective training latencies (§P<0.001). Untreated Tg mice do not show significant differences between training and retention latencies (P>0.05). The retention latencies of untreated Tg mice significantly differ from the retention latencies of all the other groups (#P<0.001). (B) ORT: in the T2 trial the discrimination index of untreated Tg mice significantly differ from the discrimination index of all other groups (*P<0.05). The dotted line indicates the chance level performance; Data are reported as mean values ± S.E.M. Number of animals: n = 12/group.