Figure 6. Involvement of K⁺ channels in the antispasmodic effect of mangiferin.

Effects of mangiferin (10 µM) on carbachol-contracted guinea pig trachea, performed in the presence or absence of TEA (A), glibenclamide (B) or apamin (C). Each point represents the mean ± S.E.M. of 6 segments. All results are expressed as a percentage of the contractile response induced by 2.5 µM carbachol. *p<0.05 compared with vehicle-treated tissues.