Figure 7. Involvement of Voltage-dependent calcium channels in the protective effect of mangiferin.

Effect of mangiferin (0.01–10 µM) on the contractile response triggered after the cumulative application of calcium to tracheal rings mounted in calcium-free high K⁺ (60 mM) Krebs’ solution. Each point represents the mean ± S.E.M. from 6 segments. The magnitude of the contractile tension induced by calcium on tracheal preparations is expressed as a percentage of the contractile response evoked by 2.5 µM carbachol. *p<0.05 compared with vehicle-treated tissues.