Table 1. Characteristics of Patients with Hypercholesterolemia and Healthy Control Subjects Before Atorvastatin Treatment.
| Variablea | Control Subjects (n = 7) | Patients (n = 7) | P-value |
| Age (y) | 38±7 | 50±7 | 0.006 |
| Sex (F/M) | 2/5 | 2/5 | 1 |
| BMI (kg/m2) | 23±4 | 40±6 | 0.001 |
| Cholesterol (mg/dL) | 155.3±30 | 223.9±39 | 0.003 |
| TG (mg/dL) | 59.0±23 | 158.3±50 | 0.001 |
| HDL-C (mg/dL) | 57.6±12 | 47.0±13 | 0.15 |
| VLDL-C (mg/dL) | 11.8±5 | 31.6±10 | 0.001 |
| LDL-C (mg/dL) | 86.1±21 | 154.6±20 | <0.001 |
| L5 (%) | 2.3±1 | 8.1±2 | <0.001 |
| [L5]b (mg/dL) | 1.9±1 | 12.6±4 | <0.001 |
a
Data are shown as the number or as the mean ± standard deviation. BMI, body mass index; TG, triglyceride; HDL-C, high-density lipoprotein cholesterol; VLDL-C, very-low-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol.
b
[L5] = L5% × LDL-C.