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. 2013 Aug 8;8(8):e72219. doi: 10.1371/journal.pone.0072219

Table 3. Number of cases (N) and percentages of observed and expected genotypes of ESR1 PvuII, CYP2C19 and UGT2B15 in tamoxifen-treated patients.

N observed % observed N expected % expected P
ESR1 PvuII
wt/wt 22 32 20.4 29.5 0.43
wt/vt 31 45 34.2 49.6
vt/vt 16 23 14.4 20.8
Total 69 100 69 100
CYP2C19
wt/wt 57 83 55.7 80.7 0.09
wt/*2 10 14 12.6 18.2
*2/*2 2 3 0.7 1
Total 69 100 69 100
UGT2B15
wt/wt 20 29 19.8 28.8 0.94
wt/*2 34 49 34.4 49.7
*2/*2 15 22 14.8 21.5
Total 69 100 69 100