Table 3.
Synergistic Effects between IL12B and HLA-B∗52:01 in Each Study
| Study |
RERI |
AP |
SI |
|||
|---|---|---|---|---|---|---|
| (95% CI) | p | (95% CI) | p | (95% CI) | p | |
| Genome scanning | 2.90 (0.60–5.20) | 0.014 | 0.50 (0.23–0.78) | 0.00034 | 2.57 (1.08–6.09) | 0.032 |
| Replication study | 3.87 (1.70–6.05) | 0.00049 | 0.62 (0.42–0.81) | 4.7 × 10−10 | 3.76 (1.51–9.32) | 0.0043 |
| Combined study | 3.46 (1.90–5.02) | 1.4 × 10−5 | 0.58 (0.42–0.73) | 1.0 × 10−12 | 3.24 (1.72–6.11) | 0.00028 |
Abbreviations are as follows: RERI, relative excess risk; AP, attributable proportion; SI, synergy index; CI, confidence interval.