Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Expression of RNF8 in colorectal cancer cell lines. The expressions of RNF8 were different for cancer cell lines evaluated by RT-PCR (A) and Western blotting (B). In the cell line with the highest expression, SW1417, blockage of RNF8 by the siRNA technique significantly decreased the IC50 of oxaliplatin (C). The solid line indicates SW1417, and the dashed line indicates SW1417 siRNA. The experimental techniques are described in “Patients and Methods”.
