Micrographs represent CD45 immunoreactivity in the frontal cortex (CX) and hippocampus (HPC) of rTg4510 mice following Sc Aβ (A, B, n=5) or OLIGO injections (C, D, n=5). Staining density was analysed as percent of stained area for each region and graphed as ratio of ipsilateral to the contralateral side (E, F). The scale bar represents 50μm.