Figure 8. Infusion of oligomers increased immunostaining for pS202/T205 tau.
Micrographs of pS202/T205 immunoreactivity in the CA1 and EC of rTg4510 mice infused with saline (A, B) or OLIGO (C, D) are presented. Insets in panels A and B represent higher magnification images of p-tau localization in the cell body and dendrites of neurons. Staining density was analysed as percent of stained area for each region (E, F). Scale bars represent 200 μm in each panel, and 50 μm in the insets. Student t-test; ** p< 0.01, n=6.