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editorial
. 2013 Jan 7;15(2):169–173. doi: 10.1038/aja.2012.143

Table 1. Studies showing a decline in semen parameter values (total sample size=18 109).

Year First author Sample size Study period Location Major findings
1995 Auger19 1351 1973–1992 France 1. Mean volume: no change.
          2. Mean sperm concentration declined 2.1% per year from 89 million per ml to 60 million per ml.
          3. Percent motile sperm decreased 0.6% per year.
          4. Percent normal sperm decreased by 0.5% per year.
1996 Irvine20 577 1984–1995 Scotland 1. Sperm concentration fell from 98 million per ml in older cohort to 78 million per ml among donors born after 1970.
          2. Total motile sperm count fell from 169 million to 129 million.
          3. Concentration declined 2.1% per year.
          4. Motility increased 0.18% per year.
1996 Adamopoulos21 2385 1977–1993 Greece 1. Total sperm count declined from 154.3 million to 130.1 million.
          2. No significant drop in semen volume.
1998 Bonde22 1196 1986–1995 Denmark 1. Median sperm concentration dropped from 63 million per ml in men born 1937–1949 to 52 million per ml in men born 1970 and later.
          2. Median total sperm count dropped from 206 million and 117 million respectively.
1999 Bilotta23 1068 1981–1995 Italy 1. 31% decline in sperm concentration over the study period.
          2. 8% decline in motility.
          3. 9% decline in sperm with ‘typical morphology'.
2003 Almagor24 2638 1990–2000 Israel 1. Sperm count declined by 5.2 million each year.
          2. Motility declined by 0.5% per year.
2005 Lackner25 7780 1986–2003 Austria 1. Study population was infertile men
          2. Decline in sperm concentration from 27.75 million per ml in 1986 to 4.60 million per ml in 2003.
2012 Splingart26 1114 1976–2009 France 1. No decline in semen volume.
          2. Decrease in total sperm count from 443 million in 1976 to 300 million in 2009.
          3. Motility declines from 64% to 49%.
          4. Decline in percent of ‘normal forms' from 67% to 26%.