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editorial
. 2013 Jan 7;15(2):169–173. doi: 10.1038/aja.2012.143

Table 3. Studies presenting ambiguous results (total sample size=26 007).

Year First author Sample size (N) Study period Location Major findings
1995 Comhaire46 360 NA Belgium 1. Motility and morphology exhibited ‘highly significant decreases'.
          2. Total sperm count did not decrease.
          3. 40% of donors after 1990 exhibited ‘subnormal' sperm compared with only 5% of group investigated before 1980.
1996 van Waeleghem47 416 NA Belgium 1. Volume increased slightly.
          2. Mean concentration declined by 12.4 million per ml in study period.
          3. Sperm count was unchanged.
          4. Normal morphology decreased from 39.2% in 1977–1980 to 26.6% in 1990–1995.
1996 de Mouzon48 7714 1989–1995 France 1. No decline in sperm counts when data were analyzed by year of collection.
          2. Sperm counts declined ‘regularly' for men born from 1950 to 1975.
1997 Zheng49 8608 1968–1992 Denmark 1. Semen quantity and quality did not decline with increasing year of birth during the entire period from 1922 to 1972.
          2. From 1950 onward there was a gradual decline in sperm count and normal sperm forms but not in semen volume.
          3. Decline in total sperm count was 1.9 million per ml per year of advancing year of birth.
1999 Ulstein50 5180 1975–1994 Norway 1. Two subgroups of study subjects showed declines in semen parameters.
          2. Subgroup of men with previous children did not show decline in semen parameters.
2010 Mukhopadhyay51 3729 1981–1985–2000–2006 India 1. Mean semen concentration rose from 84×106 per ml in 1980s to 87×106 per ml in 2000s.
          2. Volume declined slightly from mean of 2.97 ml to 2.7 ml.
          3. Motility declined slightly from 60.6% to 58%.

Abbreviation: NA, not applicable.