Table 3. Percentages of secretory cells with positive cytoplasmic, membrane and nuclear staining (the values in parentheses are those with strong intensity, that is, with 2+ and 3+).
| SSTRs | Nep | PCa | |||
|---|---|---|---|---|---|
| RP 3 | RP 4/5 | RP 3 | RP 4/5 | TURP HR | |
| Cytoplasm | |||||
| Subtype 1 | 80.3±10.3 (6.4±4.9) | 81.8±3.5 (5.5±2.9) | 80.5±14.8 (8.7±7.2) | 86.5±8.4 (8.6±4.6) | 41.4±25.8 (1.0±3.1) |
| Subtype 2 | 81.2±14.5 (6.0±4.0) | 83.1±7.3 (6.4±3.4) | 83.8±9.2 (10.2±4.7) | 93.7±6.8 (11.7±4.9) | 66.3±14 (9.0±4.3) |
| Subtype 3 | 81.9±10.2 (8.1±6.1) | 82.6±4.5 (7.5±1.7) | 83.2±14.9 (10.5±7.4) | 87±24.1 (10.1±3.7) | 61.7±22.8 (4.6±6.1) |
| Subtype 4 | 84.3±9.7 (5.1±2.9) | 86.2±3.2 (5.5±3.7) | 86.7±9.9 (13.9±13.8) | 96.1±5.5 (15.2±7.8) | 50.5±19.6 (0±0) |
| Subtype 5 | 78.2±8.2 (4.7±2.6) | 80.2±5.3 (5.1±2.7) | 80.7±13.1 (6.1±6.5) | 83.9±14.5 (10.9±5.6) | 37.0±7.3 (0±0) |
| Membranea | |||||
| Subtype 3 | 54.1±22.5 (13.8±8.6) | 54.9±11.1 (12.8±6.6) | 6.3±9.3 (0.2±0.4) | 8.5±4.0 (0.4±0.8) | 3.5±4.3 (0±0) |
| Subtype 4 | 9.2±11.3 (0.2±0.4) | 9.9±9.9 (0.3±0.6) | 5.8±3.5 (0±0) | 8.2±0.6 (0±0) | 6.7±1.5 (0±0) |
| Nuclearb | |||||
| Subtype 4 | 20.2±8.8 (0±0) | 21.8±15.2 (0±0) | 33.7±25.1 (0±0) | 35.3±16.5 (0.3±0.9) | 37.1±16.2 (0±0) |
| Subtype 5 | 45.4±7.4 (0±0) | 47.2±22.1 (0±0) | 26.8±15.3 (0±0) | 32.5±20.0 (1.0±2.1) | 19.5±16.1 (0±0) |
Abbreviations: Nep, normal epithelium; PCa, prostate cancer; RP, radical prostatectomy; SSTR, somatostatin receptors; TURP HR, transurethral resection of the prostate hormone-refractory prostate cancer.
Values are shown as mean±s.d.
a
Immunohistochemistry for subtypes 1, 2 and 5 was negative.
b
Immunohistochemistry for subtypes 1, 2 and 3 was negative.