Table 1. Demographics of patients and their lab data.
Conventional IVF cycle | ICSI cycle (ejaculated sperm) | ICSI cycle (TESE or MESA sperm) | |||||||
---|---|---|---|---|---|---|---|---|---|
GG | AG | AA | GG | AG | AA | GG | AG | AA | |
No. of couples | 196 | 146 | 32 | 162 | 111 | 21 | 92 | 81 | 24 |
Female age (year) | 33.3±4.5 | 32.5±4.1 | 34.1±4.0 | 32.1±4.3 | 31.3±4.9 | 32.3±5.2 | 29.6±4.7 | 29.0±3.8 | 28.7±5.1 |
Male age (year) | 34.7±5.5 | 34.5±4.9 | 36.1±5.1 | 34.2±5.4 | 33.5±6.2 | 33.9±5.4 | 30.9±6.0 | 30.5±4.0 | 30.5±5.5 |
Mean no. of oocytes per cycle | 11.2±6.7 | 11.5±6.7 | 10.8±7.4 | 13.8±8.5 | 12.6±7.0 | 13.4±9.6 | 15.1±8.1 | 15.4±7.7 | 16.6±7.5 |
MII rate (%) | — | — | — | 81.3 | 80.1 | 80.0 | 79.8 | 80.7 | 82.2 |
Total fertilization rate per injected oocytes (%) | 68.7 | 67.1 | 62.5 | 66.4 | 61.7 | 62.1 | 63.4 | 62.0 | 61.3 |
Total rate of high quality embryo (%) | 73.8 | 75.3 | 71.6 | 75.0 | 70.5 | 65.9 | 85.4 | 77.0 | 75.6 |
Mean fertilization rate per cycle (%) | 68.1±22.2 | 68.2±20.5 | 60.3±26.4 | 67.2±21.3 | 63.1±23.2 | 63.5±28.9 | 66.1±19.6 | 61.1±22.2 | 61.4±18.6 |
Mean rate of high quality embryo (%) | 72.3±25.1 | 74.6±26.5 | 61.6±34.3 | 76.1±26.1 | 74.6±28.6 | 56.9±36.9%a | 82.3±19.0 | 74.0±25.6 | 72.3±20.3 |
Abbreviations: ICSI, intracytoplasmic sperm injection; IVF, in vitro fertilization; MESA, microsurgical epididymal sperm aspiration; MII rate, metaphase II oocytes rate; TESE, testicular sperm extraction.
Mann–Whitney U test, P<0.05 (GG versus AA; AG versus AA, respectively).