Fig. 5.
In the presence of 5 ug/ml of sCD4, GP vaccine sera neutralized subtype C virus TV1.29 predominantly via anti-V3 antibodies. A V3 peptide (30 ug/ml) matched to the subtype C vaccine immunogen was used to inhibit the V3-mediated neutralization by the sera. A scrambled V3 peptide had no inhibitory effect (not shown).