Table 2. IVF and embryo transfer outcomes for HBV-positive and HBV-negative groups.
| Variable | Positive (n=587) | Negative (n=587) | P value |
|---|---|---|---|
| Age of wives (year) | 31.4±4.9 | 31.4±4.9 | NS |
| Female BMI (kg m−2) | 22.0±3.2 | 22.0±3.3 | NS |
| Duration of infertility (year) | 4.9±3.4 | 4.7±3.3 | NS |
| Times of IVF–ET/ICSI–ET (cycle) | 1.1±0.4 | 1.1±0.4 | NS |
| Primary infertility (n, %) | 181 (30.8) | 183 (31.2) | NS |
| Distribution of infertile factors (n, %) | |||
| Total number of husbands with sperm problems | 415 (71.3) | 379 (65.1) | 0.025 |
| Total number of wives with tubal blockage | 503 (85.7) | 485 (82.6) | NS |
| Total number of wives with ovulation failure | 14 (2.4) | 20 (3.4) | NS |
| Total number of wives with endometriosis | 77 (13.1) | 62 (10.6) | NS |
| Total number of couples with unexplained infertility | 14 (2.4) | 13 (2.2) | NS |
| Duration of stimulation (d) | 9.6±2.2 | 9.7±2.1 | NS |
| Total dose of gonadotropin used (IU) | 2670±1085 | 2659±1056 | NS |
| Serum E2 levels on day of hCG injection (pmol l−1) | 1 1669±7024 | 1 2161±7634 | NS |
| No. of retrieved oocytes | 12.5±6.4 | 12.6±6.4 | NS |
| No. of embryos transferred in cycles by ET | 2.1±0.5 | 2.1±0.5 | NS |
| 2PN fertilisation rate (%) | 4508/7144 (63.1) | 4803/7623 (63.0) | NS |
| High-grade embryo rate (%) | 2757/4633 (59.5) | 2907/4943 (58.8) | NS |
| Implantation rate (%) | 284/1140 (24.9) | 296/1108 (26.7) | NS |
| Clinical pregnancy rate (%) | 217/535 (40.5) | 210/521 (40.3) | NS |
| Cancellation rate (n, %) | 52 (8.9) | 66 (11.2) | NS |
Values are presented as mean±s.d.
Abbreviations: BMI, body mass index; E2, estradiol; ET, embryo transfer; HBV, hepatitis B virus; hCG, human chorionic gonadotrophin; ICSI, intracytoplasmic sperm injection; IVF, in vitro fertilisation; NS, not significant; 2PN, two-pronuclear.