Figure 7. Vβ5+ Treg expansion in FV infection is IL-2 independent.
A) The absolute number of CD4+ cells expressing Foxp3 in naïve mice (white bars), FV-infected mice (2 wpi) (black bars) and mice infected with FV and treated with IL-2 blocking antibody treatment (gray bars). The absolute number of splenic CD4+Foxp3+ T cells expressing B) Vβ5− and C) Vβ5+ at 2 wpi. D) Infection levels in the spleen as measured by infectious center assays. There was no significant difference between the groups by Student’s t test. E) The absolute number of activated (CD43+) CD8+ T cells in mice from treated and untreated groups as indicated.