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Diagrammatic representation of the experimental protocols used in this study. (A) Preventive and systemic protocol; (B) preventive and topical eye drop protocol; (C) treatment and topical eye drop protocol; (D) effects of DIZE versus dorzolamide; and (E) the role of Mas in the effects of DIZE. IHC, immunohistochemistry; TEM, transmission electron microscopy.
