Table 3. Evaluation of the three groups after 12 months.
| ADT group (n=46) | Non-ADT group (n=37) | Control group (n=50) | P value* | ||||
|---|---|---|---|---|---|---|---|
| 12 months | Change | 12 months | Change | 12 months | Change | ||
| Testosterone (ng dl−1) | 25±9 | −424±149 | 356±127 | −53±66 | 394±129 | −31±68 | <0.001 |
| Waist circumference (cm) | 88.5±6.3 | 1.8±3.4 | 85.9±6.0 | 0.3±2.8 | 86.7±5.7 | 0.7±2.3 | 0.035 |
| Fasting insulin (mU l−1) | 26.99±6.94 | 11.78±3.91 | 18.02±3.97 | 1.77±3.48 | 16.88±3.09 | 2.43±2.94 | <0.001 |
| Fasting glucose (mmol l−1) | 6.11±0.75 | 0.88±0.68 | 5.46±0.51 | 0.11±0.51 | 5.52±0.37 | 0.32±0.44 | <0.001 |
| Total cholesterol (mmol l−1) | 5.32±0.61 | 0.50±0.44 | 4.86±0.68 | 0.06±0.38 | 4.97±0.46 | 0.32±0.29 | <0.001 |
| Triglyceride (mmol l−1) | 1.59±0.42 | 0.04±0.32 | 1.62±0.52 | 0.15±0.40 | 1.49±0.31 | 0.09±0.25 | 0.344 |
| HDL (mmol l−1) | 1.51±0.42 | 0.19±0.23 | 1.38±0.31 | 0.10±0.29 | 1.32±0.24 | 0.07±0.20 | 0.048 |
| LDL (mmol l−1) | 3.46±0.72 | 0.43±0.72 | 3.09±0.53 | 0.22±0.43 | 3.14±0.48 | 0.06±0.41 | 0.003 |
Abbreviations: ADT, androgen deprivation therapy; HDL, high-density lipoprotein; LDL, low-density lipoprotein.
*One-way analysis of variance was used to compare “change from baseline” among the three groups.