Table 1. EC50 (µmol l−1) values with 95% confidence intervals of SEC-induced relaxation in rabbit corpora cavernosa (RbCC), aortic rings, tracheal chains and duodenum.
Experimental condition | Tissue | EC50 (µmol l−1) |
---|---|---|
Precontracted with phenylephrine (10 µmol l−1) | Corpus cavernosum | 13.6 (9.8–19.0)* |
Precontracted with phenylephrine (10 µmol l−1) | Aortic rings E+ | 52.4 (32.2–164.8) |
Precontracted with phenylephrine (10 µmol l−1) | Aortic rings E− | 59.6 (24.6–144.6) |
Precontracted with carbamylcholine (10 µmol l−1) | Tracheal rings | 120.4 (66.0–219.6) |
Spontaneous contractility | Duodenum | 153.6 (66.2–356.4) |
Abbreviations: E+, endothelium-intact; E−, endothelium-denuded.
*P<0.05, compared with other four groups, analysis of variance (ANOVA) followed by Tukey–Kramer test.