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Effect of Ginkgo biloba extracts (GBE) on the BKCa channel whole-cell currents in human corporal smooth muscle cells. (a) Current–voltage relationships obtained using a 500-ms ramp pulse from −100 to +60 mV. Membrane currents were recorded before and 5 min after administration of GBE. (b) GBE-stimulated currents were inhibited by 1 mmol l−1 tetraethylammonium (TEA), a BKCa channel selective inhibitor. (c) Summary of the means±s.e. of peak whole-cell currents at +60 mV (n=12).
