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. Author manuscript; available in PMC: 2014 Jun 1.
Published in final edited form as: Arterioscler Thromb Vasc Biol. 2013 Mar 28;33(6):1230–1237. doi: 10.1161/ATVBAHA.113.301436

Figure 6. Cocaine and cocaine metabolites do not increase intracellular cAMP levels.

Figure 6

HUVEC were grown to confluence and incubated with the indicated agonists (dDAVP 4μg/ml, forskolin 2μM, and histamine 50μM) or serum free media (untreated). Cocaine and metabolite concentrations indicated are in μg/ml. Intracellular cAMP concentration was determined in cell lysates for each condition as indicated. The results are expressed as means +/− SEM. * Tukey’s HSD test, as compared to untreated cells (p < 0.05).