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. Author manuscript; available in PMC: 2014 Sep 1.
Published in final edited form as: J Mol Cell Cardiol. 2013 May 30;62:144–152. doi: 10.1016/j.yjmcc.2013.05.014

Figure 3. Fractional contribution (Fc) to acetyl-CoA by 13C-NMR.

Figure 3

(A) Fc to acetyl-CoA with systemic infusion (S), including large unlabeled endogenous contribution. (B) Fc to acetyl-CoA with intracoronary infusion (IC). In comparison with S, Fc of [2,4,6,8-13C4]octanoate markedly increased with CON and ECMO. In both the systemic and intracoronary infusion groups, LCFA oxidation significantly increased with ECMO when compared to CON. White, Fc of unlabeled endogenous substrates; dark gray, Fc of [2-13C]lactate; light gray, Fc of [2,4,6,8-13C4]octanoate; black, Fc of [U-13C]LFCAs. (C) Anaplerotic component relative to CAC flux. Values are means ± SE; n = 5-6 per group. *: P < 0.05, †: P < 0.01 vs CON, ‡: P < 0.01 vs S.