Table 1.
Parameters of cardiac function at beginning and endpoints for each group.
| CON-S (n = 6) | ECMO-S (n = 5) | CON-IC (n = 6) | ECMO-IC (n = 5) | |||||
|---|---|---|---|---|---|---|---|---|
| Baseline | Endpoint | Baseline | Endpoint | Baseline | Endpoint | Baseline | Endpoint | |
| Hemoglobin, g/dL | 9.1 ± 0.2 | 8.6 ± 0.3 | 9.1 ± 0.7 | 6.7 ± 0.5*† | 9.5 ± 0.2 | 9.1 ± 0.2 | 9.9 ± 0.2 | 7.1 ± 0.3*† |
| HR, BPM | 87 ± 2 | 91 ± 3 | 97 ± 6 | 110 ± 9 | 96 ± 6 | 103 ± 9 | 96 ± 3 | 117 ± 7 |
| CO, L/min | 1.2 ± 0.1 | 1.3 ± 0.1 | 1.1 ± 0.1 | 1.3 ± 0.1 | 1.3 ± 0.1 | 1.3 ± 0.2 | 1.2 ± 0.1 | 1.2 ± 0.1 |
| Mean SBP, mmHg | 66 ± 3 | 58 ± 2 | 66 ± 4 | 52 ± 2* | 59 ± 5 | 57 ± 1 | 58 ± 3 | 54 ± 3 |
| DP, mmHg | 24 ± 2 | 24 ± 2 | 22 ± 1 | 5 ± 1*† | 25 ± 2 | 24 ± 3 | 27 ± 4.0 | 7 ± 2*† |
| LVEDP, mmHg | 10 ± 1 | 9 ± 1 | 11 ± 1 | 7 ± 1*† | 7 ± 1 | 7± 1 | 7 ± 1 | 5 ± 1*† |
| dP/dt max, mmHg/s | 906 ± 76 | 1023 ± 82 | 905 ± 74 | 611 ± 141† | 810 ± 50 | 892 ± 54 | 887 ± 38 | 754 ± 127 |
| dP/dtmin, mmHg/s | −1442 ± 72 | −1147 ± 85 | −1622 ± 126 | −657 ± 67*† | −1442 ± 240 | −1326 ± 100 | −1320 ± 35 | −662 ± 97*† |
| MVO2, μmol/min/g | 1.9 ± 0.1 | 1.8 ± 0.1 | 1.9 ± 0.2 | 1.4 ± 0.1* | 2.2 ± 0.3 | 1.9 ± 0.2 | 2.3 ± 0.2 | 1.7 ± 0.2* |
CO, mean value of cardiac output; Mean SBP, mean systemic blood pressure; DP, developed pressure (aortic systolic pressure – diastolic pressure); LVEDP, left ventricular end diastolic pressure; dP/dt, first derivative of LV pressure; MVO2, myocardial oxygen consumption. Values are means ± SE; n = 5-6 per group.
*
P < 0.05 vs baseline.
†
P < 0.05 vs Control.