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. 2013 Aug 9;8(8):e71479. doi: 10.1371/journal.pone.0071479

Figure 4. The density and total number of CA1 pyramidal cells in the right dorsal hippocampus.

Figure 4

Immunocytochemistry (NeuN antibody in conjunction with DAB) and the optical fractionator method were used to establish cell density within the CA1. Cell density (a) was multiplied by the volume of the dorsal CA1 SP to establish total number (b). The data was analysed using a one-way ANOVA and Tukey’s post-hoc test. The Aβ25–35+FGL group had a significantly greater density (a) and total number (b) of pyramidal cells in the CA1 SP than compared with the Aβ25–35 alone and the FGL alone groups, whilst the control group had significantly more pyramidal cells than all of the other groups, regardless of the groups cell density. (*P<0.05, **P<0.01). Mean ± SEM, n = 4.