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. 2013 Aug 9;8(8):e71650. doi: 10.1371/journal.pone.0071650

Figure 3. Effects of eye-drop applications of Tat-µCL on photoreceptor cell death in S334ter rats.

Figure 3

A) TUNEL staining of retinal sections of S334ter rats treated with eye-drops containing Tat-µCL. Eye-drops containing vehicle (PBS) or 20 mM Tat-µCL were administered from PN 13 to 17 days. Eyes were enucleated at PN 18 days. Retinal sections were stained with TUNEL (green) and DAPI (blue). B) Quantitative analysis of the number of TUNEL-positive cells in the ONL at PN 18 days. Data are expressed as means ± standard deviation (n = 12 eyes (6 rats) per group). ***P<0.001 versus vehicle (t-test). Abbreviations: ONL, outer nuclear layer; INL, inner nuclear layer; GCL, ganglion cell layer.