Skip to main content
. 2013 Aug 9;8(8):e71650. doi: 10.1371/journal.pone.0071650

Figure 5. Effects of eye drop applications of Tat-µCL on photoreceptor cell death in P23H rats.

Figure 5

A) TUNEL of retinal sections of P23H rats treated with eye-drops containing Tat-µCL. Eye-drops containing saline (PBS), 1 mM Tat-µCL in saline, or 1 mM Tat-µCL in 0.1% HA were administered from PN 14 to 49 days. Eyes were enucleated at PN 30, 40, or 50 days. Retinal sections were stained with TUNEL (green) and DAPI (blue). B) Quantitative analysis of the number of TUNEL-positive cells in the ONL at PN 30, 40, and 50 days. Data are expressed as means ± standard deviation (n = 12 eyes (6 rats) per group). *P<0.05 and **P<0.01 versus the saline-treated group (t-test). Abbreviations: ONL, outer nuclear layer.