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. 2013 Aug 9;8(8):e71650. doi: 10.1371/journal.pone.0071650

Figure 7. Effects of eye-drop applications of Tat-µCL on thickness of retinal layers in P23H rats.

Figure 7

A) Eye-drops containing saline (PBS), 1 mM Tat-µCL in saline, or 1 mM Tat-µCL in 0.1% HA were administered from PN 14 to 89 days. Eyes were enucleated at PN 30, 70, or 90 days. Retinal sections were stained with hematoxylin and eosin. B) Quantitative analysis of the thickness of ONL at PN 30, 70, and 90 days. Data are expressed as means ± standard deviation (n = 12 eyes (6 rats) per group). *P<0.05, **P<0.01, and ***P<0.001 versus the saline-treated group (t-test). Abbreviations: ONL, outer nuclear layer; INL, inner nuclear layer; GCL, ganglion cell layer.